Is there a way to have the CC Calendar do appointment notice pop-ups at various intervals prior to the appointment time similar to those in Outlook?

The trick here is to get FileMaker to run a script every so often- once you can do that, you can have a script that "finds" upcoming appointments or finds them and then emails you about them.

In order to run a script like this (every x minutes, for instance), you'll need something like the Events Plugin. In many of our installations, we have a simple FileMaker client running this plugin as an unattended "agent". This machine can do email notifications, run reports, etc.

You'll wonder how you ever lived without one. =)